Author: Site Editor Publish Time: 11-11-2022 Origin: Site
Quick Answer
How long does Botulax last once mixed?
Reconstituted Botulax should be stored at 2°C to 8°C (36°F to 46°F) and used within 24 hours, according to available Botulax product information.Best practice: Reconstitute the product close to the planned treatment time and keep the reconstituted solution refrigerated when not in use.
If you're a medical professional or clinic owner using botulinum toxin in your practice, you've likely worked with—or at least heard of—Botulax. Among the many brands on the market like Nabota, Riztox (Hutox), and others, Botulax botulinum toxin has earned its spot as South Korea's most trusted botulinum toxin, holding a nearly 40% market share and topping domestic sales for four years in a row.
Why is that? Simple. Botulax offers high purity, reliable results at low doses, and a solid safety record with very few adverse incidents. But even the best product loses its punch if it's not stored and handled correctly. The key point is straightforward: once Botulax has been reconstituted with sterile, preservative-free 0.9% sodium chloride, it should be kept refrigerated at 2°C to 8°C and used within 24 hours according to available Botulax product information.
So let's answer the big question—and a few important ones around it:
Once Botulax has been reconstituted with sterile, preservative-free 0.9% sodium chloride, the reconstituted solution should be stored in a refrigerator at 2°C to 8°C (36°F to 46°F) and used within 24 hours.
The 24-hour window is the key handling point for clinics. While published stability research on botulinum toxin products may investigate longer storage periods, the product-specific handling instructions should take priority in clinical practice. For Botulax, clinics should follow the applicable product information and avoid extending the labeled in-use period simply because the solution has remained refrigerated.
For this reason, the simplest clinic workflow is to reconstitute Botulax close to the planned treatment time, maintain refrigerated storage at 2°C to 8°C when it is not being used, and discard any remaining solution according to the applicable product instructions.
✅ Pro Tip: Want a full Botulax usage and storage protocol PDF for your team? Contact us and we'll send it right to your inbox.
Yes, refrigeration is essential—before and after reconstitution.
Before mixing: Keep the vial in the fridge (2°C to 8°C). This ensures the toxin's stability and prevents early degradation.
After mixing: If not used immediately, the solution should be refrigerated again and used within 24–72 hours max. Most professionals prefer to use it on the same day to guarantee full effectiveness.
If you're managing a high-volume clinic, pre-scheduling appointments to align with reconstitution time is a smart move. It reduces waste and ensures patients always receive the most potent product.
| Stage | Storage guidance |
|---|---|
| Unopened vial | Refrigerate at 2°C to 8°C |
| After reconstitution | Refrigerate at 2°C to 8°C |
| Recommended in-use period after reconstitution | Within 24 hours |
| Freezing | Do not freeze |
| Unused reconstituted product | Follow the applicable product instructions for disposal |
These points should always be checked against the current product information supplied with the specific Botulax presentation used by the clinic.
Use sterile, preservative-free 0.9% sodium chloride (saline)
The common dilution ratio is:
100 Units Botulax + 2.5 mL saline = 4 Units per 0.1 mL
Gently swirl—don't shake—the vial to dissolve the powder
⚠️ Professional use only: Always reconstitute and inject Botulax under sterile conditions and with proper anatomical knowledge. It's not something to DIY.
For reconstitution guidelines, check: How Much Saline Should Be Mixed With Botulax?
Ready to stock Botulax at competitive wholesale prices? Get a quote from our supply team today.
Unopened Botulax should be stored under the temperature conditions specified for the product, typically refrigerated at 2°C to 8°C. Available product information lists a shelf life of 36 months from the manufacturing date when stored under the specified conditions.
The unopened shelf life and the in-use period after reconstitution are different. Once the vial has been reconstituted, the applicable in-use period is much shorter and should not be treated as an extension of the original 36-month shelf life.
Botulax is intended for use by appropriately trained healthcare professionals. Clinics should follow the current product information for the specific Botulax presentation in use, including storage conditions, reconstitution, administration, and disposal requirements.
Botulax has rightfully earned its reputation as South Korea's #1 botulinum toxin, offering high purity, reliable effects, and patient satisfaction at a competitive price. But even the best toxin can underperform if not stored and handled correctly.
So here's the bottom line:
✅ Reconstitute Botulax with preservative-free saline.
✅ Use it within 24 hours—ideally on the same day.
✅ Refrigerate it at all times, never freeze.
✅ Don't push its limits just to save a few dollars—your results depend on it.
✉ Want to become an Botulax distributor or clinic partner? Reach out today and join hundreds of professionals worldwide choosing smarter aesthetic solutions.
Whether you're using Botulax or other korean botulinum toxin brands, consistent technique and safe storage practices are what truly deliver world-class results.
Reconstituted Botulax should be refrigerated at 2°C to 8°C and used within 24 hours according to applicable Botulax product information.
Yes. When the reconstituted solution is not being used immediately, it should be kept refrigerated at 2°C to 8°C and used within the applicable 24-hour in-use period.
Do not freeze reconstituted Botulax. Clinics should follow the storage and handling instructions supplied with the specific product presentation.
Available product information lists a 36-month shelf life for unopened Botulax when stored under the specified refrigerated conditions. Always check the manufacturing date and the product labeling for the vial in use.
Storage requirements can vary by product and presentation. For this reason, clinics should follow the product-specific instructions rather than assuming that the handling period for one botulinum toxin brand automatically applies to another.
