There is no Botulinum toxin gel products right now. Botulinum toxin gel is in clinical trials and not yet approved by the U.S. Food and Drug Administration.
The common appearance of botulinum toxin products is Lyophilized Powder. Botulinnum toxin is made of Clostridium botulinum, is widely distributed in nature and can be found in soil. But there is also an liquid type botulinum toxin.
Botulinum Toxin is really known because many celebrities use Botulinum Toxin for beauty treatments. Botulinum toxin enters the blood circulation through the mucosa, acts on the cranial nerve nucleus and the peripheral neuromuscular junction and the autonomic nerve endings, inhibits the release of acetylcholine, and causes muscle relaxation paralysis. It is precisely because of this structure, function and mechanism of action of botulinum toxin that people began to use the toxin as a drug to treat blepharospasm, spastic torticollis, spastic dysphonia and other diseases. The muscles are paralyzed, so that the muscles do not contract, thereby removing wrinkles. Botulinum Toxin is used for cosmetic purposes, and it is necessary to pay attention to the dosage, injection site, etc., and it should be done by a specialized doctor.
"Purification" is the most important part of all steps, because the native botulinum toxin is a high molecular weight complex. In addition to the botulinum toxin that produces the effect, it also contains other complex proteins that are not related to the effect. Antibodies are produced, making the treatment less effective. Therefore, staff will wait until the complex protein in Botulinum Toxin approaches zero before making the first dispensing. After a series of complex process, the staff will freeze the purified botulinum after packaging, and the pharmaceutical factory will take the product to another room to thaw it when receiving the order.
Innotox is the world's first newly developed liquid injectable form of botulinum toxin type A, which was approved by the KFDA in Korea in 2013. Innotox is a ready-to-use sterile liquid with a concentration of 4U/0.1ml. It can avoid the risk of excessive injection of botulinum toxin or contamination caused by improper ratio of normal saline. Innotox botulinum toxin ultimately improve the safety and efficacy of treatment.
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