| Availability: | |
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NeoSkin/NeoEye
PNPURE™
Medical Disclaimer: PNPURE™ injectable polynucleotides are intended strictly for licensed aesthetic practitioners and medical professionals. Patient results vary based on skin condition, protocol design, and biological response.
The average cost of PNPURE™ polynucleotides ranges from $39 to $90 per vial for wholesale clinic procurement, while retail patient treatment sessions typically range from $350 to $700 per session, depending on clinic location, combination protocols, and injection technique. Request a tailored quote or free consultation to receive an accurate, clinic-level price.
| Category | Product Spec | Target Indication | Clinic Wholesale Price (per vial) | Typical Patient Session Price |
| PNPURE™ NeoSkin | 2.5% PN (1260–1570 kDa) | Full-face collagen renewal, scar remodeling | $39 – $90 | $400 – $750 |
| PNPURE™ NeoEye | PN + HA + Amino Acids + Carnosine | Periorbital fine lines, dark circles, thin skin | $29 – $80 | $350 – $650 |
| PNPURE™ Combo Protocol | NeoSkin + NeoEye Dual Treatment | Total facial & periocular rejuvenation | Custom Package | $700 – $1,200 |
Note: Wholesale tiers are subject to order volume and regional distributor agreements. Request a customized quote for exact tier rates.

PNPURE™ represents the next generation of injectable skin regeneration therapy. Formulated with high-purity polynucleotides (1260–1570 kDa) derived from premium Pacific salmon DNA and refined through PUNEXT™ multi-stage purification, it delivers exceptional safety, bio-compatibility, and clinical performance. Each injection revitalizes skin from within, promoting structural repair, long-term hydration, and visibly improved texture.
True purity begins at the source. The DNA used in PNPURE™ is harvested from salmon inhabiting pristine waters around latitude 35°N in the Pacific Ocean — one of the world’s cleanest marine environments. Each fish is raised under antibiotic-free, sterile aquaculture conditions to ensure complete biological consistency. Through the proprietary PUNEXT™ purification process, proteins and impurities are meticulously removed, leaving only >99% pure polynucleotides. This exceptional purity ensures both safety and effectiveness with every treatment.

PNPURE NeoSkin offers an intensive 2.5% concentration of active polynucleotides, accelerating tissue recovery and collagen synthesis. Its high molecular weight creates a 3D dermal matrix, supporting deep and lasting rejuvenation.
PNPURE NeoEye is a delicate yet powerful formula that combines PN, hyaluronic acid, amino acids, and carnosine to nourish the sensitive eye area. It enhances firmness and elasticity while minimizing irritation, restoring youthful brightness and smoothness.

| Comparison point | PNPURE™ NeoSkin | PNPURE™ NeoEye |
|---|---|---|
| Product positioning | Formulated for skin-quality treatment applications | Formulated for the eye area |
| Formulation information | The stated formulation contains 2.5% polynucleotides | The stated formulation includes polynucleotides, hyaluronic acid, amino acids, and carnosine |
| Quotation details | Confirm the applicable packaging, quantity, and unit price | Confirm the applicable packaging, quantity, and unit price |
| Best next step | Request a quotation for the required NeoSkin configuration | Request a quotation for the required NeoEye configuration |
Clients who choose PNPURE™ typically notice improved smoothness and hydration within 2–4 days after their first session. By the second polynucleotide treatment, firmness and elasticity increase while fine lines fade. After completing the full program, skin appears lifted, luminous, and resilient. Clinical studies demonstrate that PNPURE™ activates fibroblast regeneration more effectively and maintains its effects longer than conventional non-crosslinked HA products. Thousands of patients and aesthetic professionals worldwide trust PNPURE™ for superior and lasting rejuvenation.

When evaluating the polynucleotides treatment price, it is essential to understand that you are investing not just in a procedure, but in a scientifically advanced solution that delivers measurable, enduring improvements. For a detailed comparison, you may also explore our guide on polynucleotide treatment cost. PNPURE™ provides premium clinical results at a price that remains accessible, with competitive wholesale options for clinics and partners. Each treatment plan is personalized according to your skin’s needs, ensuring optimal efficacy and value.

Experience the transformative benefits of medical-grade skin regeneration with PNPURE™. Our team of specialists ensures every treatment is performed under the highest safety and efficacy standards.
Book your free confidential consultation today — receive a comprehensive skin evaluation and a transparent, customized treatment plan with a clear quote. Limited-time free consultations are now available for new clients.
Invest in your skin’s future with PNPURE™ — where purity, performance, and personalized care meet.
Q: What is the typical wholesale cost of PNPURE™ for medical clinics?
A: Wholesale pricing for licensed aesthetic clinics starts at competitive entry rates around $29–$39 per vial for tiered volume purchases. Official distributor quotes depend on regional shipment terms and order quantities.
Q: What is included in the price of PNPURE™ treatments?
A: Clinic pricing typically covers the PNPURE™ product, professional administration, follow-up, and any recommended combination products. Wholesale pricing for clinics excludes administration fees.
Q: Can I see an itemized quote for polynucleotide treatment cost?
A: Yes. Use “Request Quote” and include your clinic location and desired package; we return a clear, itemized quote with options.
Q: How many vials of PNPURE™ are required for a full face treatment?
A: Most clinical protocols recommend 1 to 2 vials per session for full-face treatments, and 1 vial for targeted periorbital (eye) applications. A standard full rejuvenation course consists of 3 sessions.
Q: How does PNPURE™ compare to traditional Hyaluronic Acid skin boosters in cost and longevity?
A: While standard HA skin boosters primarily provide temporary surface hydration lasting 1–3 months, PNPURE™ polynucleotides stimulate active fibroblast regeneration and tissue repair, delivering structural collagen improvements that persist for 6 to 12 months.
Q: Are volume discounts or starter packages available for new aesthetic practices?
A: Yes. Dermax offers starter kits and tiered bulk pricing for certified clinics and medical distributors. Customized itemized quotes can be generated upon verifying professional credentials.
Q: What is the downtime after a PNPURE™ polynucleotide injection?
A: Downtime is minimal. Micro-papules on the skin surface typically diminish within 24 to 48 hours. Patients are advised to avoid strenuous exercise, direct sun exposure, and saunas for the first 48 hours.
Q: How quickly do patients notice visible results from PNPURE™?
A: Hydration and skin smoothness improvements are commonly noted within 2 to 4 days post-first injection. Structural firming, fine line reduction, and elasticity restoration peak approximately 2 to 3 weeks after the second session.
Q: Is the polynucleotide treatment price refundable?
A: Refund and return policies depend on product condition and local regulations. Dermax supports a clear after-sales process — contact customer service for case-specific support.
Disclaimer: Please note that packaging designs may vary, however, we always aim to display the most current design. Most of our products are intended for use by licensed medical professionals. By purchasing, you agree to provide proof of medical or professional credentials upon request. The medical device products are not intended for personal or home use and we strongly recommend that medical professionals review the instructions thoroughly to understand the specific contradictions and any necessary precautions.
