PDRN skin boosters use purified DNA fragments from salmon to stimulate skin regeneration. Delivered via mesotherapy, these injectables activate collagen and elastin production, improving skin elasticity, texture, and radiance—with minimal downtime. In this article, we'll explore how PDRN works, its advantages over HA boosters, and practical use cases including Mesocel® PDRN Injection.
PDRN (Polydeoxyribonucleotide) is a DNA compound extracted from salmon, originally used for wound healing. In aesthetics, it's injected into the skin to activate fibroblasts and repair tissue. It's highly biocompatible—about 98% similar to human DNA—and works to improve texture, smooth wrinkles, and accelerate healing.
PDRN boosts collagen and elastin by activating fibroblasts, simulating the skin's natural repair process. It also improves hydration, promotes blood circulation, and reduces inflammation. The result is firmer, plumper, and healthier-looking skin from within—not just surface-level changes.
Firmer, smoother skin with fewer lines and wrinkles
Improved hydration and skin tone
Reduction in acne scars and rough texture
Calms redness and supports sensitive skin
Long-lasting results—often visible for 6 to 9 months
Many patients report visible improvement after just a few sessions, with results that build over time.
Before the procedure, a topical numbing cream is applied to ensure comfort. During the treatment, PDRN is injected into the skin using a tiny needle to minimize downtime. While individual recovery varies, most people experience only mild redness and small bumps right after the session, which usually fade within an hour.
Mesocel® PDRN Injection is a premium skin rejuvenation treatment that combines high-purity salmon-derived PDRN with carefully selected ingredients to deliver visible, long-lasting results.
The PDRN used in Mesocel® is extracted from sea trout DNA and purified to over 99%, making it highly biocompatible and safe. Every batch undergoes strict quality checks to ensure it's free from harmful substances and safe for all skin types.
In addition to PDRN, Mesocel® includes:
Non-crosslinked hyaluronic acid for deep hydration
Type III collagen peptides to support skin structure and elasticity
This powerful blend works together to repair the skin, improve elasticity, and reduce fine lines and wrinkles. Many users report smoother, firmer, and more radiant skin after just a few sessions. The treatment is well-tolerated, with only mild, temporary redness or small papules that fade quickly—making it a reliable choice for both clinics and patients.
A standard treatment plan for PDRN skin boosters includes:
Initial Phase: 3–4 sessions spaced 3–4 weeks apart to deeply saturate the skin.
Optional Extra Session: A 4th treatment may be added 4–6 weeks later for more stubborn skin concerns.
Maintenance Phase: 3–4 sessions per year, ideally every 2–3 months, to maintain and extend results.
Injection Technique: Consistent injection depth and even spacing are essential for best results and minimal product loss.
Follow-Up: Skin usually shows noticeable improvement 4–6 weeks after the final session, with ongoing collagen regeneration lasting for several months.
Clinics can tailor the plan depending on individual skin conditions, but this structure offers a reliable framework for consistent results.
PDRN skin boosters like Mesocel® are changing the game in skin rejuvenation—delivering real, regenerative results far beyond basic hydration.
If you're a clinic or distributor in the U.S. or Europe, now is the perfect time to expand your treatment menu with Mesocel® PDRN Injection.
Safe, effective, and backed by clinical results
Designed for professionals, with wholesale supply available
Trusted by aesthetic experts for long-term skin repair
Contact us today to learn more about bulk pricing, ordering, and integrating Mesocel® into your aesthetic solutions. Give your clients smoother, firmer, and more youthful-looking skin—with results they'll keep coming back for.
