Author: Site Editor Publish Time: 01-13-2026 Origin: Site
Calcium hydroxylapatite (CaHA) fillers are biocompatible injectable dermal fillers composed of microscopic CaHA particles suspended in a gel carrier. Derived from a mineral naturally present in human bones and teeth, CaHA is widely used in aesthetic medicine for facial volumization, contour enhancement, and wrinkle correction.
Once injected, the gel component delivers immediate lifting and shaping, while the solid CaHA microspheres provide a stable scaffold that stimulates fibroblast activity and new collagen formation. This dual-action mechanism distinguishes CaHA fillers from purely volumizing options, allowing them to deliver natural-looking, longer-lasting results that continue to improve skin firmness and structural support over time.
CaHA filler is commonly selected for areas requiring structural support, definition, and gradual skin quality improvement.
Midface and cheek augmentation
Jawline and chin contouring
Nasolabial fold correction
Temple hollowing
Hand rejuvenation
Clinical outcomes from CaHA fillers often persist for 18 to 24 months, with some patients experiencing visible benefits beyond two years. Longevity depends on injection depth, treatment area, patient metabolism, and practitioner technique.
Calcium hydroxylapatite fillers have a strong safety record when administered by trained medical professionals. Because CaHA is non-animal and biocompatible, the risk of hypersensitivity reactions is low.
· Mild swelling or bruising
· Temporary redness at injection sites
CaHA fillers are generally not recommended for superficial injections, areas with very thin skin, or patients with active infections, autoimmune disorders affecting connective tissue, or known hypersensitivity to filler components.
Understanding how CaHA compares with other injectable fillers helps both patients and practitioners select the most appropriate treatment approach.
Calcium hydroxylapatite fillers provide a balance between immediate volumization and long-term collagen stimulation. Hyaluronic acid fillers primarily act as space-occupying gels that attract water for instant volume but do not actively stimulate collagen. Poly-L-lactic acid (PLLA) fillers, on the other hand, rely almost entirely on gradual collagen induction, with minimal immediate correction.
Because of this, CaHA fillers are often chosen when both instant contouring and sustained tissue remodeling are desired within a single treatment plan.
Feature | CaHA Fillers | Hyaluronic Acid Fillers | PLLA Fillers |
Immediate results | Yes | Yes | Minimal |
Collagen stimulation | Yes | No | Yes |
Typical longevity | 18–24+ months | 6–12 months | 18–24 months |
Structural support | High | Moderate | Low initially |
Ideal use cases | Contouring, lifting | Fine lines, hydration | Gradual volumization |
For clinicians exploring CaHA-based options, CHArmacy® caha filler is formulated to combine immediate aesthetic correction with long-term collagen stimulation. Its formulation integrates calcium hydroxylapatite microspheres with a viscoelastic gel system to support both short- and long-term outcomes.
CHArmacy® incorporates precisely engineered CaHA microspheres produced using advanced manufacturing technology, enabling stable tissue support and controlled biodegradation. The inclusion of a high-viscoelasticity gel component allows for immediate wrinkle filling and contour refinement, while the CaHA microspheres gradually promote collagen formation around the treated area.
This balanced design makes CHArmacy® suitable for practitioners seeking predictable shaping, durable results, and a natural post-treatment appearance—without compromising affordability or clinical performance. For inquiries about our product range, don’t wait to contact us.
Are calcium hydroxylapatite fillers reversible?
Unlike hyaluronic acid fillers, CaHA fillers are not enzymatically reversible. Proper patient selection and precise injection technique are essential.
Do CaHA fillers look natural?
When placed at appropriate depths, CaHA fillers produce firm yet natural-looking results that evolve gradually as collagen forms.
Who is an ideal candidate for CaHA fillers?
Patients with moderate volume loss, skin laxity, or contour deficiency who desire longer-lasting results may benefit from CaHA fillers.
Peer-reviewed literature on calcium hydroxylapatite dermal fillers (PubMed)
International Society of Aesthetic Plastic Surgery (ISAPS) clinical resources
Aesthetic dermatology textbooks on biostimulatory fillers
