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· Product Name: Devolux®
· Composition: Poly-L-Lactic Acid(PLLA)
· Concentration: 160mg/vial
· Packing: 1vial per box
· Application Areas: Cheeks, Chin, Jawline, Nasolabial Folds, Tear Troughs, etc
· Storage Instructions: Store under controlled room temperature between 0°C and 25°C.
· Shelf Life: 2 years
· Certification: CE, MSDS
· Country of Origin: China
· Manufacturer: Dermax Medical Co., Ltd
· OEM: Yes
· For professional use only.
Devolux®
When choosing between different collagen-stimulating fillers, many practitioners compare PMMA collagen dermal fillers with poly-L-lactic acid (PLLA) fillers. Although both approaches aim to restore volume and improve skin quality, they differ significantly in longevity, safety profile, reversibility, and the way they interact with the body's collagen production.
PMMA fillers contain permanent microspheres that remain in the tissue for many years, while PLLA fillers such as Devolux® gradually stimulate the body's own collagen and are naturally absorbed over time. Understanding these differences can help clinics and distributors select the most suitable option for facial and body rejuvenation.
PMMA (polymethyl methacrylate) collagen dermal filler is a semi-permanent or permanent injectable filler composed of microscopic PMMA beads suspended in a collagen-based carrier. After injection, the collagen gel provides immediate volume while the PMMA microspheres remain in the tissue and act as a scaffold for collagen formation.
Because PMMA particles are not absorbed by the body, results may last for several years. This long duration makes PMMA fillers attractive for patients seeking long-lasting correction. However, permanent fillers also require careful patient selection and precise injection techniques.
PMMA fillers are commonly used for:
Deep facial folds
Acne scars
Nasolabial folds
Volume restoration
Certain body contouring procedures
Both PMMA and PLLA belong to the category of collagen-stimulating fillers, but they work through different mechanisms.
| Feature | PMMA Collagen Filler | Devolux® PLLA Filler |
|---|---|---|
| Material | Polymethyl methacrylate microspheres | Poly-L-lactic acid |
| Longevity | 5 years or longer | 2–3 years |
| Collagen stimulation | Yes | Yes |
| Biodegradable | No | Yes |
| Reversibility | Limited | Naturally absorbed |
| Volume effect | Immediate and permanent | Progressive and natural |
| Texture | Firmer | Softer and more natural |
| Maintenance | Minimal | Periodic treatments |
| Safety profile | Requires experienced injector | Favorable safety profile |
| Suitable areas | Deep folds and scars | Face and body volume restoration |
Unlike permanent PMMA fillers, Devolux® PLLA gradually restores lost volume by stimulating the body's own collagen synthesis. Many practitioners appreciate the subtle and natural progression of results, especially in patients seeking harmonious facial rejuvenation.
Although PMMA fillers provide extremely long-lasting correction, many aesthetic practitioners increasingly favor PLLA-based fillers for several reasons.
PLLA stimulates collagen production gradually. Instead of creating an abrupt change, volume restoration develops progressively over several months, often resulting in a softer and more natural appearance.
Unlike PMMA microspheres, poly-L-lactic acid is biodegradable. After stimulating collagen formation, the material is gradually metabolized by the body.
Because PLLA treatments are usually performed over multiple sessions, physicians can customize the degree of correction according to individual needs.
In clinical practice, PLLA fillers are frequently selected for:
Temples
Midface
Jawline
Chin
Neck
Hands
Buttocks
Hip dips
PMMA lip filler treatments have been reported, but they are relatively uncommon compared with absorbable fillers.
The lips are highly dynamic structures that undergo constant movement. Because PMMA particles remain permanently in the tissue, some practitioners may prefer biodegradable fillers for lip enhancement in order to maintain flexibility and allow future adjustments.
For patients seeking collagen stimulation and gradual enhancement, PLLA-based treatments may offer a more adaptable approach.
Several PMMA filler brands have been used worldwide for long-term soft tissue correction.
Examples include:
Bellafill Brand
PrimeFill Brand
Linnea Safe Brand
These products are designed to provide durable correction through permanent PMMA microspheres.
At the same time, an increasing number of clinics are incorporating collagen stimulators based on poly-L-lactic acid. Compared with permanent fillers, PLLA products offer long-lasting but non-permanent results, allowing practitioners to adapt treatment plans as facial aging progresses.
Devolux® is Dermax's collagen-stimulating poly-L-lactic acid filler developed for natural and long-lasting volume restoration.
Key advantages include:
Each vial contains 160 mg of poly-L-lactic acid, providing strong collagen stimulation for both facial and body applications.
The powder can be prepared within approximately five minutes, improving efficiency in busy aesthetic practices.
Advanced particle engineering contributes to uniform suspension and predictable treatment outcomes.
A complete treatment session consisting of three procedures may deliver results lasting 2–3 years.
Rather than acting as a permanent implant, Devolux® encourages the body to rebuild its own collagen network, producing gradual and natural-looking enhancement.
Although competitively priced, Devolux® maintains high manufacturing standards and is suitable for clinics seeking reliable and cost-effective collagen-stimulating fillers.
| Item | Details |
|---|---|
| Product Name | Devolux® PLLA Filler |
| Active Ingredient | Poly-L-lactic Acid |
| Content | 160 mg per vial |
| Injection Layer | Between subdermal and superficial fat |
| Treatment Protocol | Three sessions |
| Second Treatment | 1–1.5 months after first treatment |
| Third Treatment | 1.5–2 months after second treatment |
| Duration | 2–3 years |
| Shelf Life | 2 years |
| Storage | Room temperature |
| Certifications | CE, ISO, GMP |
PLLA fillers are commonly used for patients seeking gradual and natural volume restoration.
Common treatment indications include:
Age-related facial volume loss
Deep folds and wrinkles
Sunken temples
Hollow cheeks
Jawline contouring
Chin enhancement
Hand rejuvenation
Buttock augmentation
Hip dip correction
Because collagen stimulation occurs progressively, multiple sessions are generally recommended for optimal outcomes.
Disclaimer: Please note that packaging designs may vary, however, we always aim to display the most current design. Most of our products are intended for use by licensed medical professionals. By purchasing, you agree to provide proof of medical or professional credentials upon request. The medical device products are not intended for personal or home use and we strongly recommend that medical professionals review the instructions thoroughly to understand the specific contradictions and any necessary precautions.
Dermax's Devolux poly-L-lactic acid Devolux is optimal for correcting deep creases/wrinkles and folds in the face, Sunken Eyes body that occur over time. Areas treated include:
Founded in 2003, Dermax has more than two decades of experience in aesthetic medicine and serves customers in over 80 countries worldwide.
The company operates multiple manufacturing facilities and maintains international warehouses in the United States, Germany, the United Kingdom, South Korea, and China, enabling faster local delivery and reliable supply for clinics, distributors, and aesthetic professionals.
By combining competitive pricing with consistent quality standards, Dermax aims to provide accessible and dependable medical aesthetic solutions for the global market.
PMMA filler is a collagen-stimulating injectable containing polymethyl methacrylate microspheres suspended in a carrier gel. The microspheres remain in the tissue and provide long-term structural support.
PMMA particles are not biodegradable, making PMMA one of the longest-lasting filler options available. Results may persist for many years.
PMMA fillers generally last longer than PLLA fillers. PMMA may provide correction for five years or more, while a complete Devolux® PLLA treatment session typically lasts two to three years.
Common PMMA filler brands include Bellafill Brand, Metacrill Brand, and Linnea Safe Brand.
PMMA lip filler procedures exist, but many practitioners prefer absorbable fillers for lip enhancement because they provide greater flexibility and easier future adjustments.
Many physicians favor PLLA fillers because they stimulate natural collagen production, provide gradual results, and are biodegradable rather than permanent.
No. Devolux® is a biodegradable poly-L-lactic acid filler. It stimulates collagen formation and is gradually absorbed by the body over time.
Yes. PLLA fillers are classified as collagen-stimulating fillers because they promote the body's own collagen production instead of merely occupying space.
