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PDRN Injection vs. Salmon DNA Injection: PDRN vs. PN

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*Choosing the Right Regenerative Treatment for Your Skin Goals*  


Key Takeaways at a Glance


PDRN = Best for wound healing & anti-inflammation
Salmon DNA (PN) = Ideal for collagen boost & hydration
Mesocel® PDRN = Advanced 36-ingredient formula for anti-aging

(Scroll down for clinical comparison table ↓)


Understanding the Science


1. Salmon PDRN Injections


What It Is:

Polydeoxyribonucleotide (PDRN) extracted from salmon sperm DNA with specific molecular weight (50-1500 kDa)


How It Works:

→ Binds to A2A adenosine receptors to accelerate tissue repair→ Increases VEGF production for enhanced blood flow

→ Reduces inflammatory cytokines (TNF-α, IL-6)


Proven Benefits:

✔ 68% faster wound healing vs. placebo (J Dermatolog Treat, 2021)
✔ 42% reduction in post-acne erythema
✔ Stimulates Type I collagen synthesis


2. Salmon DNA (PN) Injections


What It Is:

Polynucleotides (PN) from salmon sperm with longer chains (>1500 kDa)


How It Works:

→ Acts as fibroblast growth factor (FGF) booster
→ Creates 3D mesh in dermis for structural support
→ Increases hyaluronic acid production


Proven Benefits:

✔ 39% improvement in skin elasticity after 3 sessions
✔ 2.5x higher hydration retention vs. HA alone
✔ Reduces dynamic wrinkles by 55%


Head-to-Head Comparison

Feature

PDRN Injection

Salmon DNA (PN) Injection

Source

Fragments of salmon DNA

Whole salmon sperm DNA

Molecular Size

50-1500 kDa

>1500 kDa

Best For

Reduces redness and soothes irritation.lmproves skin tone and reduces hyperpigmentation

Age-related volume loss, dryness

Pain Level

Low (contains lidocaine)

Moderate

Results Duration

8-12 weeks

8-12 weeks


Clinical Case Studies


Case 1: Acne Scarring (PDRN)


Patient: 28F with icepick scars

Protocol: Monthly PDRN microneedling × 2

Results: Scar depth reduced by 52%

PDRN before and after 1 treatment

Case 2: Menopausal Skin (PN)


Patient: 52F with crepey neck skin

Protocol: PN injections every 3 weeks × 3

Results: Fitzpatrick scale improvement from 4→2


Why Choose Mesocel® PDRN?


Our premium formula combines:

✦ PDRN

✦ Hyaluronic acid

✦ 8 amino acids

✦ 6 vitamins

✦ 5 minerals

✦ 7 others


Therapeutic Programs:


The first 3 sessions, 4 weeks apart

The 4th and 5th sessions, 4-6 weeks apart

The following sessions, 2-3 months apart


Visible Changes in 3 Phases:


Day 1-7: Reduced redness

Week 2-4: Improved texture

Month 2-3: Collagen remodeling

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Partner with Mesocel® PDRN for Your Business Growth


As the exclusive manufacturer and distributor of Mesocel® PDRN, we provide premium regenerative solutions for clinics, medspas, and aesthetic professionals worldwide.


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Contact: +86 16764319411

Email: support@dermaxmed.com

For bulk orders, OEM requests, or distributor opportunities, contact our team today! CONTACT US!