Author: Site Editor Publish Time: 05-06-2024 Origin: Site
Nabota is a popular botulinum toxin type A used by aesthetic and medical professionals worldwide. Whether you’re treating glabellar lines, forehead wrinkles, or therapeutic indications like post-stroke spasticity, proper reconstitution is critical to ensure safety, accuracy, and efficacy.
In this blog, we'll walk you through how to mix Nabota botulinum toxin 100 Units with 0.9% saline solution, explain why dilution matters, and provide a helpful Nabota dilution chart to guide your practice.
Nabota is a botulinum toxin type A injectable manufactured by Daewoong Pharmaceutical in South Korea. It's FDA-approved (marketed as Jeuveau® in the U.S.) and known for its high purity and low immunogenicity.
NABOTA has been manufactured using a patented manufacturing process to insure impurities have been removed as much as possible, resulting in a highly purified product. It's commonly used to reduce facial wrinkles such as glabellar lines, crow's feet, and forehead lines, and also for certain therapeutic indications under the guidance of medical professionals.
Before using Nabota, it must be reconstituted (mixed) with a 0.9% sodium chloride solution (saline) to prepare it for injection.
Before you start, gather the following supplies:
Item | Details |
Nabota 100U vial | Comes as a freeze-dried white powder |
0.9% sodium chloride solution | Preservative-free sterile saline |
3 mL or 5 mL syringe | For drawing and injecting saline |
30G or 32G injection needle | For intramuscular or intradermal injections |
21G or 23G mixing needle | For drawing saline into the vial |
Alcohol swabs | For disinfecting vial rubber stopper |
Gloves and mask | For aseptic preparation |
Then, let's look at How to mix Nabota botulinum toxin, Mixing Nabota 100 units, also known as Jeuveau or Newtox, involves reconstituting the lyophilized product with a saline solution. Here's a general guide on how to do it:
1. Prepare the Saline Solution: Use a 0.9% non-preservative sterile saline solution.
2. Dilution Ratio: The standard dilution is 100 Units of Nabota to 2.5 mL of saline, resulting in a concentration of 4 Units per 0.1 mLh.
3. Reconstitution Process:
• Insert the needle into the Nabota vial.
• Slowly inject the saline into the vial. There might be a vacuum present, so inject slowly to avoid forming bubbles.
• Gently mix the Nabota until it is completely clear and no particles are visible.
Use the Nabota reconstituted solution within 24 hours, and always store it in a refrigerator at 2–8°C (36–46°F). Discard any unused portion after 24 hours.
The reconstitution process for Nabota (botulinum toxin type A) or any other botulinum toxin product should only be performed by qualified healthcare professionals who are trained in the administration of such treatments.
How To Mix Nabota 100 units
Here's a reference table showing how dilution affects unit concentration per 0.1 mL—useful for calculating doses.
Saline Volume (mL) | Units per 0.1 mL | Best Use Case |
1.0 mL | 10 Units | Small muscles or therapeutic treatments |
2.0 mL | 5 Units | Common for glabellar, forehead, crow's feet |
2.5 mL | 4 Units | Precise aesthetic applications |
4.0 mL | 2.5 Units | Wider diffusion, larger treatment zones |
Tip: For most aesthetic facial treatments, 2.0–2.5 mL dilution provides an ideal balance between precision and spread.
Nabota is a brand of botulinum toxin type A, used for various medical and cosmetic purposes, including the treatment of wrinkles, muscle spasms, and certain medical conditions.
Botulinum Toxin Type A: Nabota contains botulinum toxin type A, a neurotoxin produced by the bacterium Clostridium botulinum. This toxin blocks nerve signals in muscles, leading to temporary muscle paralysis.
Unit Measurement: Like other botulinum toxin products, Nabota is measured in units rather than volume. One unit of botulinum toxin represents the biological activity needed to produce a defined effect.
Storage: Nabota should be stored in a refrigerator at temperatures between 2°C to 8°C (36°F to 46°F) to maintain its stability. It should be protected from light and should not be frozen.
Duration of Action: After injection, patients typically begin seeing results in 2–4 days, with full effect in 7–10 days. The effects of Nabota usually last 3–4 months, though this may vary depending on the patient, dose, and area treated.
Indications: Nabota is indicated for various medical and cosmetic purposes, including the treatment of facial wrinkles (such as glabellar lines, forehead lines, and crow's feet), muscle spasms (such as cervical dystonia and spasticity), and other conditions.
Side Effects: Common side effects of Nabota injections may include temporary redness, swelling, bruising, or pain at the injection site. Less common side effects may include headache, flu-like symptoms, or eyelid drooping. Serious side effects are rare but can occur, particularly if the toxin spreads beyond the injection site.
Proper mixing of Nabota is essential for safe and effective results. By following the correct dilution methods and handling guidelines, you ensure optimal outcomes for your patients—and minimize the risk of side effects.
Whether you're treating a single patient or preparing multiple vials for your clinic, precision, hygiene, and product knowledge are key.
As a trusted Nabota supplier, Dermax provides authentic Nabota 100 Units and Nabota 200u to licensed clinics and professionals worldwide. We also offer:
Expert guidance for product use
Global cold-chain shipping
Certificates of authenticity
No minimum order requirements
Want to Order Nabota?
Contact Dermax today for wholesale pricing, usage support, or to place your next order with confidence.
Please ensure that you are eligible to purchase and use such products and that you comply with all local regulations and laws. Always consult with a healthcare professional before purchasing or using medical products like Nabota.
