According to published studies at home and abroad and our personal injection experience, if the injection dose is more than 10ml, its efficacy can be maintained for an average of 1.5 years. Although the metabolism of hyaluronic acid is continuous, its absorption rate will gradually accelerate in the later stage, so in order to maintain the best state, I personally recommend supplementary injection 1 year after the first injection, mainly for the following three reasons:
First, delay the metabolic rate of hyaluronic acid. The research and clinical experience of hyaluronic acid filling tell us that supplemental injection when hyaluronic acid is not completely metabolized can delay its metabolism;
Second, save costs. When replenishing injections, the injection dose will be significantly reduced compared with the first time, so the cost of consumables will also be reduced;
Third, a large number of studies have confirmed that in the first year after the first injection, the metabolic rate of hyaluronic acid is generally low, and the metabolic rate gradually accelerates after 1 year, so injection is most appropriate at this time point.