Botulinum toxin is injected into the muscles whose contractions cause wrinkles, such as between the eyebrows (frown lines) and the lines that radiate from the corner of the eyes (crow's feet). The effects of Botox usually last for 3 to 4 months.
Wrinkles that remain at rest may require filler to fill-in or lift up skin that is depressed. Prominent folds around the mouth, nose, and chin are the most commonly treated. Hyaluronic acid, a natural occurring sugar polymer, is the most common filler used. Most fillers are temporary, providing improvement for around 4 to 6 months.