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100 units 200 units
Nabota®
Nabota, developed by Daewoong Pharmaceutical Co., Ltd., is a type A botulinum toxin that has received FDA approva. This marks the first Korean botulinum toxin to be introduced in the American market. Nabota offering the same toxin handling process. The Nabota series comprises of two products: Nabota 100ui and Nabota 200ui.
Nabota 100ui Botulinum Toxin Type A
Each vial contains
Active ingredient: Clostridium botulinum toxin type A 100 units(U)
(Korean Minimum Requirement for Biopharmaceutical Product)
Stabilizer: Human serum albumin 0.5mg (Korean Minimum Requirement for Biopharmaceutical Product)
Isotonic agent: Sodium chloride (USP) 0.9mg
* One unit(U) of NABOTA corresponds to the calculated median intraperitoneal lethal dose (LD50) in mice.
Indication and Usage
Temporary improvement of forehead lines associated with corrugator and/or procerus muscle activity in adult patients between 20 to 65 years old
Upper limb spasticity after stroke in adult patients above 18 years old
Storage
The unopened lyophilized vial should be stored in a freezer (blow -5°C) or refrigerator (2~8°C).
Smoothing wrinkles in the area of the eyebrows, nasolabial folds, wrinkles near the eyes and mouth, periorbital and perioral zones
Blepharospasm elimination
Hyperhidrosis elimination
Botulinum toxin lifting
NABOTA 100ui is botulinum toxin product with high purity which was developed with the technology of approximately 30 years' bioproduct experience and patented manufacturing technique.
Patented Technology
NABOTA botulinum toxin was developed with 30 years of experience in biotechnology.
NABOTA ensures the quality of international standards via its own patented purification process (Patent registration KR 10-1339349 in 2013)
Reduced Impurity
NABOTA 100ui is a highly purified product manufactured with a patentedpurification process from which impurities are removed as much as possible.
Overseas Expansion
Excellence in the quality of NABOTA 100ui has led to contracts to export the finished product to about 90 countries including the United States and 28 European countries.
Proven Efficacy & Safety
The efficacy and the safety of NABOTA 100ui are proved to be comparable to other brand botulinum toxin in various clinical studies.
1. Using an appropriate syringe, draw nonpreserved sterile saline (see dilution table below). 0.9% Sodium Chloride is the recommended diluent.
2. Insert the needle and slowly inject the saline into the NABOTA vial in which vacuum is present.
3. Inject slowly and avoid forming bubbles.
4. Gently mix lyophilized NABOTA until it is completely clear and no particles are visible.
5. Record the date and time of reconstitution. The solution should be administered within 24 hours after reconstitution.
6. Reconstituted product should be stored in a refrigerator (2-8℃).
Is Nabota 100ui safe?
Yes, Nabota 100ui has undergone rigorous testing for safety and efficacy and has been approved by various health authorities, including the FDA.
What about the purity of Nabota?
Nabota is highly pure, with over 98% purity of the 900 kDa botulinum toxin. It is produced using a patented purification process.
How should Nabota 100u be used?
To achieve a concentration of 4 units per 0.1 ml, dilute 100 units of Nabota with 2.5 ml of 0.9% sterile saline without preservative. Use a 30-gauge injection needle for the procedure.
When will I see results after a Nabota treatment?
Results can be seen within 24 to 48 hours after the treatment, with the full effect typically visible within 1 to 2 weeks.
How long does a Nabota treatment last?
The effects of Nabota usually last between 3 to 6 months, varying depending on the individual and the treated area.
Are there any side effects of Nabota?
Side effects are generally mild and temporary, such as bruising, swelling, or redness at the injection site. Serious side effects are rare but can include muscle weakness or difficulty swallowing.
Can anyone receive Nabota injections?
Most adults can receive Nabota injections, but it is not recommended for pregnant or breastfeeding women, or individuals with certain neurological diseases.
How is Nabota different from other botulinum toxin brands?
Nabota is known for its high purity and stability, which can lead to a more predictable and refined outcome.
Nabota, developed by Daewoong Pharmaceutical Co., Ltd., is a type A botulinum toxin that has received FDA approva. This marks the first Korean botulinum toxin to be introduced in the American market. Nabota offering the same toxin handling process. The Nabota series comprises of two products: Nabota 100ui and Nabota 200ui.
Nabota 100ui Botulinum Toxin Type A
Each vial contains
Active ingredient: Clostridium botulinum toxin type A 100 units(U)
(Korean Minimum Requirement for Biopharmaceutical Product)
Stabilizer: Human serum albumin 0.5mg (Korean Minimum Requirement for Biopharmaceutical Product)
Isotonic agent: Sodium chloride (USP) 0.9mg
* One unit(U) of NABOTA corresponds to the calculated median intraperitoneal lethal dose (LD50) in mice.
Indication and Usage
Temporary improvement of forehead lines associated with corrugator and/or procerus muscle activity in adult patients between 20 to 65 years old
Upper limb spasticity after stroke in adult patients above 18 years old
Storage
The unopened lyophilized vial should be stored in a freezer (blow -5°C) or refrigerator (2~8°C).
Smoothing wrinkles in the area of the eyebrows, nasolabial folds, wrinkles near the eyes and mouth, periorbital and perioral zones
Blepharospasm elimination
Hyperhidrosis elimination
Botulinum toxin lifting
NABOTA 100ui is botulinum toxin product with high purity which was developed with the technology of approximately 30 years' bioproduct experience and patented manufacturing technique.
Patented Technology
NABOTA botulinum toxin was developed with 30 years of experience in biotechnology.
NABOTA ensures the quality of international standards via its own patented purification process (Patent registration KR 10-1339349 in 2013)
Reduced Impurity
NABOTA 100ui is a highly purified product manufactured with a patentedpurification process from which impurities are removed as much as possible.
Overseas Expansion
Excellence in the quality of NABOTA 100ui has led to contracts to export the finished product to about 90 countries including the United States and 28 European countries.
Proven Efficacy & Safety
The efficacy and the safety of NABOTA 100ui are proved to be comparable to other brand botulinum toxin in various clinical studies.
1. Using an appropriate syringe, draw nonpreserved sterile saline (see dilution table below). 0.9% Sodium Chloride is the recommended diluent.
2. Insert the needle and slowly inject the saline into the NABOTA vial in which vacuum is present.
3. Inject slowly and avoid forming bubbles.
4. Gently mix lyophilized NABOTA until it is completely clear and no particles are visible.
5. Record the date and time of reconstitution. The solution should be administered within 24 hours after reconstitution.
6. Reconstituted product should be stored in a refrigerator (2-8℃).
Is Nabota 100ui safe?
Yes, Nabota 100ui has undergone rigorous testing for safety and efficacy and has been approved by various health authorities, including the FDA.
What about the purity of Nabota?
Nabota is highly pure, with over 98% purity of the 900 kDa botulinum toxin. It is produced using a patented purification process.
How should Nabota 100u be used?
To achieve a concentration of 4 units per 0.1 ml, dilute 100 units of Nabota with 2.5 ml of 0.9% sterile saline without preservative. Use a 30-gauge injection needle for the procedure.
When will I see results after a Nabota treatment?
Results can be seen within 24 to 48 hours after the treatment, with the full effect typically visible within 1 to 2 weeks.
How long does a Nabota treatment last?
The effects of Nabota usually last between 3 to 6 months, varying depending on the individual and the treated area.
Are there any side effects of Nabota?
Side effects are generally mild and temporary, such as bruising, swelling, or redness at the injection site. Serious side effects are rare but can include muscle weakness or difficulty swallowing.
Can anyone receive Nabota injections?
Most adults can receive Nabota injections, but it is not recommended for pregnant or breastfeeding women, or individuals with certain neurological diseases.
How is Nabota different from other botulinum toxin brands?
Nabota is known for its high purity and stability, which can lead to a more predictable and refined outcome.
